Head-to-head
Henry Meds vs Direct Meds
Compared on semaglutide across the eight dimensions this database records. They differ on 4 of those eight. Henry Meds is cheaper on all-in semaglutide at 2.4 mg/week, though on a flat-versus-tiered matchup the cheaper program can change further up the dose ladder.
The short answer
Henry Meds is $297 a month all-in for semaglutide; Direct Meds is $297. Over twelve months that is $3,564 against $3,564. Value Scores are 60.4 and 45.9 out of 100.
Semaglutide
Plan pages: Henry Meds plans · Direct Meds plans
At 2.4 mg/week, Henry Meds is $297 a month all-in and Direct Meds is $297, identical figures. Over twelve months the totals are $3,564 (billed monthly) and $3,564 (billed monthly).
Henry Meds charges a flat $297 per month for semaglutide at every dose from 0.25 to 2.4 mg per week, so titrating upward does not change what you pay.
Direct Meds prices semaglutide by dose: $249 per month at 0.25 mg rising to $297 at 2.4 mg, a difference of $48 a month between the bottom and top of the ladder. The company publishes no price at 0.5, 1, 1.7 mg, so those doses are left blank rather than estimated.
| Dose | Henry Meds | Rank | Direct Meds | Rank | Cheaper |
|---|---|---|---|---|---|
| 0.25 mg | $297 | 25/32 | $249 | 21/32 | Direct Meds by $48 |
| 0.5 mg | $297 | 16/21 | — | — | only Henry Meds publishes |
| 1 mg | $297 | 16/21 | — | — | only Henry Meds publishes |
| 1.7 mg | $297 | 16/21 | — | — | only Henry Meds publishes |
| 2.4 mg | $297 | 22/29 | $297 | 21/29 | level |
The lead changes with the dose. Between 0.25 mg and 2.4 mg it passes to Henry Meds. Pick on the dose you expect to settle at, not the headline.
Across the 29 programs this database can rank on semaglutide, Henry Meds sits 20 of 29 on all-in monthly cost and Direct Meds sits 22. There is 1 other program priced between them. The field median is $249 and the floor is $129, so both sit above the median. Henry Meds is $168 above the cheapest semaglutide program on record. Direct Meds is $168 above the cheapest semaglutide program on record.
NovoCare Pharmacy (Wegovy), the lowest FDA-approved semaglutide channel here, is $349 a month — Henry Meds undercuts it by $52, Direct Meds by $52. Compounded products are not FDA approved; insurance can reverse that comparison.
| Plan term | Henry Meds | Direct Meds | Cheaper |
|---|---|---|---|
| Month to month | $297 | $297 | level |
| Settled dose | Henry Meds | Direct Meds | Difference |
|---|---|---|---|
| 0.25 mg | $3,564 | $2,988 | $576 apart |
| 0.5 mg | $3,564 | — | one side unpriced |
| 1 mg | $3,564 | — | one side unpriced |
| 1.7 mg | $3,564 | — | one side unpriced |
| 2.4 mg | $3,564 | $3,564 | $0 apart |
Henry Meds publishes no rate for 3-month term, 6-month term, 12-month term; Direct Meds publishes none for 3-month term, 6-month term, 12-month term. An unpublished term is not necessarily unavailable — it is unpriced in public, which you can only resolve by asking.
A titration year is not twelve months at the maintenance price. Stepping up roughly four weeks per dose before settling at 2.4 mg/week, the first twelve months work out to $3,564 on Henry Meds and $3,516 on Direct Meds — $48 apart, and a different gap from the $0 you would get by multiplying the monthly difference by twelve. The ramp is cheaper than the settled rate on whichever program prices by dose, which is why a first-year quote and a steady-state quote are not the same number.
That calculation is partial: Direct Meds publishes no price at 3 of them, so the maintenance rate stands in for the missing steps rather than a number the company has stated.
Value Scores are 60.4 for Henry Meds and 45.9 for Direct Meds, against a semaglutide category floor of $129. Henry Meds leads by 14.5 points, and the margin comes from structure rather than price alone.
| Program | Price /70 | Evidence /15 | Dose /10 | Membership /5 | Total /100 |
|---|---|---|---|---|---|
| Henry Meds | 30.4 | 15.0 | 10 | 5 | 60.4 |
| Direct Meds | 30.4 | 10.5 | 0 | 5 | 45.9 |
Where the two programs differ
Cancellation terms
Cancellation differs: Henry Meds states Cancel before renewal; bundle refunds limited, while Direct Meds states Per provider terms. Read this next to the twelve-month figures — a prepaid discount and a restrictive refund policy are the same decision.
Commitment
Henry Meds asks for Month-to-month; 6/12-month bundles prepaid; Direct Meds asks for Monthly (no commitment indicated). This is the dimension most likely to change which program is actually cheaper for you, because the lowest rates on both sides are usually attached to the longest terms.
Dose policy
Henry Meds charges one price at every dose; Direct Meds prices by dose. That difference usually matters more than the headline gap, because the tiered program's advertised figure describes the dose you start on, not the dose you settle at.
Evidence status
The two prices are not equally well evidenced. Henry Meds's figure is verified and Direct Meds's is reported. Henry Meds rests on the stronger of the two, and the Value Score below reflects that — evidence quality is worth fifteen points and is not a tiebreaker we apply after the fact.
All-in monthly
Both programs land at the same all-in monthly figure of $297, so price alone does not separate them and the decision moves to structure.
Membership fee
Neither charges a separate membership fee.
Shipping
Shipping is handled the same way by both — included in the quoted price.
Twelve-month cost
Over twelve months the totals are $3,564 for Henry Meds and $3,564 for Direct Meds. Direct Meds is lower by $0 — a figure worth checking against the cancellation terms below, because a prepaid year is only cheaper if you stay on it.
What each record says
Henry Meds Official site
Henry Meds sells compounded semaglutide by injection at $297 per month, checkout-verified, and does not sell injectable tirzepatide at all — its tirzepatide is an oral dissolving tablet sold only as a $1,047 three-month supply, with no month-to-month rate published. The widely-quoted $179 figure applies to liraglutide or to the twelve-month prepaid term, not to a standing monthly tirzepatide rate.
It names its compounding pharmacy — Tailor Made Compounding, recorded as 503A (named on dispensed materials) — which can be checked against state board licensing and FDA inspection records before you order; commitment terms are Month-to-month; 6/12-month bundles prepaid; cancellation is Cancel before renewal; bundle refunds limited; availability is stated as Most US states.
Evidence: verified — captured at checkout by our desk on the stated date, captured . Source — Checkout capture 2026-08-11: $297/month all-in, dispensed by Tailor Made Compounding. Supersedes our prior $179–$297 plan-tier range.
Watch: Corrected 2026-08-11. Our prior record showed $179/mo flat injectable tirzepatide, taken from two third-party 2026 captures. Direct verification found no injectable tirzepatide product. Henry is therefore unrankable on the tirzepatide injection-maintenance basis — an oral dissolving tablet is a different delivery route and is not scored against injectables. The semaglutide figure was corrected upward to $297 and is now checkout-verified.
Direct Meds Official site
Direct Meds offers compounded GLP-1s in multiple formats — sublingual and injectable — with all-inclusive pricing verified on its own product pages. Semaglutide runs $249–$297/mo and tirzepatide $299–$399/mo depending on format; the lower figures are for sublingual delivery.
It does not publicly name its compounding pharmacy; the record shows Partner 503A pharmacy (not publicly named), so who actually makes the medication cannot be independently verified; commitment terms are Monthly (no commitment indicated); cancellation is Per provider terms; availability is stated as Confirm at intake.
Evidence: reported — sourced from dated third-party reporting; first-party capture pending, captured . Source — rangeyourself.com, Direct Meds product pages verified 2026-07-25
Watch: Pricing varies by format and page; product-page 'all-inclusive' rates differ from homepage promo cards. Rank is based on injectable rate as primary. Reported status — RangeYourself verified 2026-07-25 on Direct Meds' own product pages.
Which molecules each one carries
Henry Meds carries semaglutide at $297 a month; lists tirzepatide (oral dissolving tablet (no injectable tirzepatide offered)) but publishes nothing rankable for it.
Direct Meds carries tirzepatide at $399 a month and semaglutide at $297 a month.
Comparable only on semaglutide: they do not both publish a rankable tirzepatide price. Switching molecule mid-treatment would mean changing provider.
What neither record tells you
Henry Meds does not publish
- no published twelve-month semaglutide rate
- no state-by-state availability list — it says Most US states
Direct Meds does not publish
- no semaglutide price at 0.5, 1, 1.7 mg per week
- no published twelve-month semaglutide rate
- no named compounding pharmacy
- no state-by-state availability list — it says Confirm at intake
- no specific cancellation or refund terms
Ask Henry Meds and Direct Meds for each of those in writing before enrolling. A gap is not evidence of a problem; it does mean nothing can be checked against it.
What would change this answer
Evidence may be upgraded. Direct Meds carries a price we have not captured at checkout. A capture would move the evidence term and could reorder these two without any price changing.
Which one suits which reader
On the lowest standing monthly rate for semaglutide, Henry Meds Official site wins this matchup. If you expect to titrate to the top of the ladder, henry meds's flat pricing is worth more than the headline gap suggests; and if you would rather trust a better-evidenced number, henry meds's price rests on stronger provenance.
Both figures should be checked at the provider's own checkout before you pay. Henry Meds's semaglutide price is verified as of 2026-08-11; Direct Meds's is reported as of 2026-07-25.
Questions
Is Henry Meds or Direct Meds cheaper for semaglutide?
Henry Meds is cheaper on all-in monthly cost at 2.4 mg/week: $297 against $297, a difference of $0 a month. All-in means the medication plus every mandatory recurring fee.
What is the twelve-month cost of Henry Meds versus Direct Meds?
Henry Meds works out to $3,564 across twelve months and Direct Meds to $3,564, on the plan terms each publishes.
Does Henry Meds or Direct Meds raise the price as the dose goes up?
Henry Meds: no, it charges one flat rate at every dose. Direct Meds: yes, it prices by dose. Where one program is flat and the other is tiered, the cheaper of the two can change as you titrate upward.
How many ways do Henry Meds and Direct Meds differ?
4 of the eight dimensions this site records: all-in monthly, twelve-month cost, dose policy, membership, shipping, commitment, cancellation terms and evidence status.
Which of Henry Meds and Direct Meds names its pharmacy?
Henry Meds does — Tailor Made Compounding. Direct Meds does not, recording only Partner 503A pharmacy (not publicly named), so who makes its medication cannot be independently verified.
How well evidenced are the Henry Meds and Direct Meds prices?
Henry Meds's semaglutide figure is verified — captured at checkout by our desk on the stated date — captured 2026-08-11. Direct Meds's is reported, captured 2026-07-25. Evidence status is worth fifteen points in the Value Score, so it is priced in rather than mentioned as an aside.
Official sources: Henry Meds official site · Direct Meds official site. Compounded tirzepatide and semaglutide are not FDA-approved products.