Head-to-head
OrderlyMeds vs ShedRx
Compared on both medications across the eight dimensions this database records. They differ on 4 of those eight. ShedRx is cheaper on all-in tirzepatide at 10 mg/week, though on a flat-versus-tiered matchup the cheaper program can change further up the dose ladder.
The short answer
OrderlyMeds is $299 a month all-in for tirzepatide; ShedRx is $289. Over twelve months that is $3,588 against $3,468. Value Scores are 67.3 and 58.7 out of 100.
Tirzepatide
Plan pages: OrderlyMeds plans · ShedRx plans
At 10 mg/week, OrderlyMeds is $299 a month all-in and ShedRx is $289 — $10 apart, or $120 across a year. Over twelve months the totals are $3,588 (billed monthly) and $3,468 (billed monthly).
OrderlyMeds charges a flat $299 per month for tirzepatide at every dose from 2.5 to 15 mg per week, so titrating upward does not change what you pay.
ShedRx prices tirzepatide by dose: $199 per month at 2.5 mg rising to $289 at 10 mg, a difference of $90 a month between the bottom and top of the ladder. The company publishes no price at 5, 7.5, 12.5, 15 mg, so those doses are left blank rather than estimated.
| Dose | OrderlyMeds | Rank | ShedRx | Rank | Cheaper |
|---|---|---|---|---|---|
| 2.5 mg | $299 | 19/31 | $199 | 7/31 | ShedRx by $100 |
| 5 mg | $299 | 9/17 | — | — | only OrderlyMeds publishes |
| 7.5 mg | $299 | 9/17 | — | — | only OrderlyMeds publishes |
| 10 mg | $299 | 13/27 | $289 | 11/27 | ShedRx by $10 |
| 12.5 mg | $299 | 9/17 | — | — | only OrderlyMeds publishes |
| 15 mg | $299 | 9/17 | — | — | only OrderlyMeds publishes |
ShedRx is cheaper at every dose where both publish a price, so the lead does not change as you titrate.
Across the 27 programs this database can rank on tirzepatide, OrderlyMeds sits 11 of 27 on all-in monthly cost and ShedRx sits 8. There are 2 other programs priced between them. The field median is $339 and the floor is $169, so both sit below the median. OrderlyMeds is $130 above the cheapest tirzepatide program on record. ShedRx is $120 above the cheapest tirzepatide program on record.
LillyDirect (Zepbound), the lowest FDA-approved tirzepatide channel here, is $449 a month — OrderlyMeds undercuts it by $150, ShedRx by $160. Compounded products are not FDA approved; insurance can reverse that comparison.
| Plan term | OrderlyMeds | ShedRx | Cheaper |
|---|---|---|---|
| Month to month | $299 | $289 | ShedRx by $10 |
| Settled dose | OrderlyMeds | ShedRx | Difference |
|---|---|---|---|
| 2.5 mg | $3,588 | $2,388 | $1,200 apart |
| 5 mg | $3,588 | — | one side unpriced |
| 7.5 mg | $3,588 | — | one side unpriced |
| 10 mg | $3,588 | $3,468 | $120 apart |
| 12.5 mg | $3,588 | — | one side unpriced |
| 15 mg | $3,588 | — | one side unpriced |
OrderlyMeds publishes no rate for 3-month term, 6-month term, 12-month term; ShedRx publishes none for 3-month term, 6-month term, 12-month term. An unpublished term is not necessarily unavailable — it is unpriced in public, which you can only resolve by asking.
A titration year is not twelve months at the maintenance price. Stepping up roughly four weeks per dose before settling at 10 mg/week, the first twelve months work out to $3,588 on OrderlyMeds and $3,378 on ShedRx — $210 apart, and a different gap from the $120 you would get by multiplying the monthly difference by twelve. The ramp is cheaper than the settled rate on whichever program prices by dose, which is why a first-year quote and a steady-state quote are not the same number.
That calculation is partial: ShedRx publishes no price at 2 of them, so the maintenance rate stands in for the missing steps rather than a number the company has stated.
Value Scores are 67.3 for OrderlyMeds and 58.7 for ShedRx, against a tirzepatide category floor of $169. OrderlyMeds leads by 8.6 points, and the margin comes from structure rather than price alone.
| Program | Price /70 | Evidence /15 | Dose /10 | Membership /5 | Total /100 |
|---|---|---|---|---|---|
| OrderlyMeds | 39.6 | 12.8 | 10 | 5 | 67.3 |
| ShedRx | 40.9 | 12.8 | 0 | 5 | 58.7 |
Semaglutide
Plan pages: OrderlyMeds plans · ShedRx plans
At 2.4 mg/week, OrderlyMeds is $149 a month all-in and ShedRx is $249 — $100 apart, or $1,200 across a year. Over twelve months the totals are $1,788 (billed monthly) and $2,988 (billed monthly).
OrderlyMeds charges a flat $149 per month for semaglutide at every dose from 0.25 to 2.4 mg per week, so titrating upward does not change what you pay.
ShedRx prices semaglutide by dose: $175 per month at 0.25 mg rising to $249 at 2.4 mg, a difference of $74 a month between the bottom and top of the ladder. The company publishes no price at 0.5, 1, 1.7 mg, so those doses are left blank rather than estimated.
OrderlyMeds is cheaper at every dose where both publish a price, so the lead does not change as you titrate.
Value Scores are 88.4 for OrderlyMeds and 54.0 for ShedRx, against a semaglutide category floor of $129. OrderlyMeds leads by 34.4 points, driven mostly by price.
Where the two programs differ
All-in monthly
ShedRx is cheaper month to month — $289 against $299, a gap of $10 every month, or $120 across a year if both rates hold.
Commitment
OrderlyMeds asks for Month-to-month available; ShedRx asks for Month-to-month. This is the dimension most likely to change which program is actually cheaper for you, because the lowest rates on both sides are usually attached to the longest terms.
Dose policy
OrderlyMeds charges one price at every dose; ShedRx prices by dose. That difference usually matters more than the headline gap, because the tiered program's advertised figure describes the dose you start on, not the dose you settle at.
Twelve-month cost
Over twelve months the totals are $3,588 for OrderlyMeds and $3,468 for ShedRx. ShedRx is lower by $120 — a figure worth checking against the cancellation terms below, because a prepaid year is only cheaper if you stay on it.
Cancellation terms
Both state the same cancellation terms: Cancel before renewal.
Evidence status
Both figures carry the same evidence status, provider-stated: taken from the provider's own published pages; checkout capture pending. Neither is stronger than the other on provenance.
Membership fee
Neither charges a separate membership fee.
Shipping
Shipping is handled the same way by both — included in the quoted price.
What each record says
OrderlyMeds Official site
OrderlyMeds runs an all-inclusive model — $149/month compounded semaglutide and $299/month compounded tirzepatide with no membership fee — placing it near the front of the no-membership pack on semaglutide.
It does not publicly name its compounding pharmacy; the record shows Partner compounding pharmacies, so who actually makes the medication cannot be independently verified; commitment terms are Month-to-month available; cancellation is Cancel before renewal; availability is stated as Most US states.
Evidence: provider-stated — taken from the provider's own published pages; checkout capture pending, captured . Source — orderlymeds.com pricing capture 2026-08-05
Watch: Tirzepatide figure is provider-stated from published pages; checkout capture pending.
ShedRx Official site
ShedRx advertises accessible entry pricing ($175 semaglutide, $199 tirzepatide) but tiers upward with dose — $249 and $289 respectively at the maintenance basis.
It does not publicly name its compounding pharmacy; the record shows Partner pharmacies, so who actually makes the medication cannot be independently verified; commitment terms are Month-to-month; cancellation is Cancel before renewal; availability is stated as Most US states.
Evidence: provider-stated — taken from the provider's own published pages; checkout capture pending, captured . Source — shedrx.com pricing capture 2026-08-05
Watch: Start-vs-maintenance spread is among the widest in the index; budget on the maintenance figure.
What neither record tells you
OrderlyMeds does not publish
- no published twelve-month tirzepatide rate
- no published twelve-month semaglutide rate
- no named compounding pharmacy
- no state-by-state availability list — it says Most US states
ShedRx does not publish
- no tirzepatide price at 5, 7.5, 12.5, 15 mg per week
- no published twelve-month tirzepatide rate
- no semaglutide price at 0.5, 1, 1.7 mg per week
- no published twelve-month semaglutide rate
- no named compounding pharmacy
- no state-by-state availability list — it says Most US states
Ask OrderlyMeds and ShedRx for each of those in writing before enrolling. A gap is not evidence of a problem; it does mean nothing can be checked against it.
What would change this answer
Neither program publishes a promotional rate with an end date, a prepaid term, or a price we have flagged for re-verification, so the comparison above is as stable as this dataset gets.
Which one suits which reader
On the lowest standing monthly rate for tirzepatide, ShedRx Official site wins this matchup. If you expect to titrate to the top of the ladder, orderlymeds's flat pricing is worth more than the headline gap suggests.
Both figures should be checked at the provider's own checkout before you pay. OrderlyMeds's tirzepatide price is provider-stated as of 2026-08-05; ShedRx's is provider-stated as of 2026-08-05.
Questions
Is OrderlyMeds or ShedRx cheaper for tirzepatide?
ShedRx is cheaper on all-in monthly cost at 10 mg/week: $289 against $299, a difference of $10 a month. All-in means the medication plus every mandatory recurring fee.
What is the twelve-month cost of OrderlyMeds versus ShedRx?
OrderlyMeds works out to $3,588 across twelve months and ShedRx to $3,468, on the plan terms each publishes.
Does OrderlyMeds or ShedRx raise the price as the dose goes up?
OrderlyMeds: no, it charges one flat rate at every dose. ShedRx: yes, it prices by dose. Where one program is flat and the other is tiered, the cheaper of the two can change as you titrate upward.
How many ways do OrderlyMeds and ShedRx differ?
4 of the eight dimensions this site records: all-in monthly, twelve-month cost, dose policy, membership, shipping, commitment, cancellation terms and evidence status.
Which of OrderlyMeds and ShedRx names its pharmacy?
Neither. OrderlyMeds records Partner compounding pharmacies and ShedRx records Partner pharmacies. Without a named pharmacy, neither program's licensing or inspection history can be checked before you order.
How well evidenced are the OrderlyMeds and ShedRx prices?
OrderlyMeds's tirzepatide figure is provider-stated — taken from the provider's own published pages; checkout capture pending — captured 2026-08-05. ShedRx's is provider-stated, captured 2026-08-05. Evidence status is worth fifteen points in the Value Score, so it is priced in rather than mentioned as an aside.
Which is cheaper for semaglutide?
OrderlyMeds, at $149 a month all-in against $249 at 2.4 mg/week. The two programs do not necessarily lead on both medications.
Official sources: OrderlyMeds official site · ShedRx official site. Compounded tirzepatide and semaglutide are not FDA-approved products.