Head-to-head
Yucca Health vs LifeMD
Compared on both medications across the eight dimensions this database records. They differ on 4 of those eight. Yucca Health is cheaper on all-in tirzepatide at 10 mg/week, though on a flat-versus-tiered matchup the cheaper program can change further up the dose ladder.
The short answer
Yucca Health is $258 a month all-in for tirzepatide; LifeMD is $746. Over twelve months that is $3,096 against $8,952. Value Scores are 73.6 and 38.6 out of 100.
Tirzepatide
Plan pages: Yucca Health plans · LifeMD plans
At 10 mg/week, Yucca Health is $258 a month all-in and LifeMD is $746 — $488 apart, or $5,856 across a year. Over twelve months the totals are $3,096 (billed monthly) and $8,952 (billed monthly).
Yucca Health charges a flat $258 per month for tirzepatide at every dose from 2.5 to 15 mg per week, so titrating upward does not change what you pay.
LifeMD charges a flat $597 per month for tirzepatide at every dose from 2.5 to 15 mg per week, so titrating upward does not change what you pay.
| Dose | Yucca Health | Rank | LifeMD | Rank | Cheaper |
|---|---|---|---|---|---|
| 2.5 mg | $258 | 13/31 | $597 | 31/31 | Yucca Health by $339 |
| 5 mg | $258 | 6/17 | $597 | 17/17 | Yucca Health by $339 |
| 7.5 mg | $258 | 6/17 | $597 | 17/17 | Yucca Health by $339 |
| 10 mg | $258 | 6/27 | $597 | 26/27 | Yucca Health by $339 |
| 12.5 mg | $258 | 6/17 | $597 | 17/17 | Yucca Health by $339 |
| 15 mg | $258 | 6/17 | $597 | 17/17 | Yucca Health by $339 |
Yucca Health is cheaper at every dose where both publish a price, so the lead does not change as you titrate.
Across the 27 programs this database can rank on tirzepatide, Yucca Health sits 6 of 27 on all-in monthly cost and LifeMD sits 26. There are 19 other programs priced between them. The field median is $339 and the floor is $169, so Yucca Health is below the median and the other is above it. Yucca Health is $89 above the cheapest tirzepatide program on record. LifeMD is $577 above the cheapest tirzepatide program on record.
LillyDirect (Zepbound), the lowest FDA-approved tirzepatide channel here, is $449 a month — Yucca Health undercuts it by $191, LifeMD by $-297. Compounded products are not FDA approved; insurance can reverse that comparison.
| Plan term | Yucca Health | LifeMD | Cheaper |
|---|---|---|---|
| Month to month | $258 | $597 | Yucca Health by $339 |
| Settled dose | Yucca Health | LifeMD | Difference |
|---|---|---|---|
| 2.5 mg | $3,096 | $8,952 | $5,856 apart |
| 5 mg | $3,096 | $8,952 | $5,856 apart |
| 7.5 mg | $3,096 | $8,952 | $5,856 apart |
| 10 mg | $3,096 | $8,952 | $5,856 apart |
| 12.5 mg | $3,096 | $8,952 | $5,856 apart |
| 15 mg | $3,096 | $8,952 | $5,856 apart |
Yucca Health publishes no rate for 3-month term, 6-month term, 12-month term; LifeMD publishes none for 3-month term, 6-month term, 12-month term. An unpublished term is not necessarily unavailable — it is unpriced in public, which you can only resolve by asking.
A titration year is not twelve months at the maintenance price. Stepping up roughly four weeks per dose before settling at 10 mg/week, the first twelve months work out to $3,096 on Yucca Health and $8,952 on LifeMD. Both programs charge one flat rate, so the ramp costs the same as any other stretch of the year.
Value Scores are 73.6 for Yucca Health and 38.6 for LifeMD, against a tirzepatide category floor of $169. Yucca Health leads by 35.0 points, driven mostly by price.
| Program | Price /70 | Evidence /15 | Dose /10 | Membership /5 | Total /100 |
|---|---|---|---|---|---|
| Yucca Health | 45.9 | 12.8 | 10 | 5 | 73.6 |
| LifeMD | 15.9 | 12.8 | 10 | 0 | 38.6 |
Semaglutide
Plan pages: Yucca Health plans · LifeMD plans
At 2.4 mg/week, Yucca Health is $146 a month all-in and LifeMD is $497 — $351 apart, or $4,212 across a year. Over twelve months the totals are $1,752 (billed monthly) and $5,964 (billed monthly).
Yucca Health charges a flat $146 per month for semaglutide at every dose from 0.25 to 2.4 mg per week, so titrating upward does not change what you pay.
LifeMD charges a flat $348 per month for semaglutide at every dose from 0.25 to 2.4 mg per week, so titrating upward does not change what you pay.
Yucca Health is cheaper at every dose where both publish a price, so the lead does not change as you titrate.
Value Scores are 89.6 for Yucca Health and 40.9 for LifeMD, against a semaglutide category floor of $129. Yucca Health leads by 48.7 points, driven mostly by price.
Where the two programs differ
All-in monthly
Yucca Health is cheaper month to month — $258 against $746, a gap of $488 every month, or $5,856 across a year if both rates hold.
Cancellation terms
Cancellation differs: Yucca Health states Cancel before renewal, while LifeMD states Cancel anytime. Read this next to the twelve-month figures — a prepaid discount and a restrictive refund policy are the same decision.
Membership fee
LifeMD charges a membership of $149 a month on top of the medication. That is already folded into the all-in figures above — it is broken out here because a membership is a recurring charge that continues even in a month you skip a shipment.
Twelve-month cost
Over twelve months the totals are $3,096 for Yucca Health and $8,952 for LifeMD. Yucca Health is lower by $5,856 — a figure worth checking against the cancellation terms below, because a prepaid year is only cheaper if you stay on it.
Commitment
Commitment terms read the same on both: Month-to-month.
Dose policy
Both hold one price across the whole dose ladder, so neither punishes titration and the monthly figures above are what you actually pay at 15 mg as well as at 2.5 mg.
Evidence status
Both figures carry the same evidence status, provider-stated: taken from the provider's own published pages; checkout capture pending. Neither is stronger than the other on provenance.
Shipping
Shipping is handled the same way by both — included in the quoted price.
What each record says
Yucca Health Official site
Yucca pairs no-membership pricing with dose-flat rates: $146/month semaglutide and $258/month tirzepatide, both all-in.
It does not publicly name its compounding pharmacy; the record shows Partner 503A pharmacies, so who actually makes the medication cannot be independently verified; commitment terms are Month-to-month; cancellation is Cancel before renewal; availability is stated as Most US states.
Evidence: provider-stated — taken from the provider's own published pages; checkout capture pending, captured . Source — yuccahealth.com pricing capture 2026-08-05
Watch: Provider-stated from published pages; checkout capture pending.
LifeMD Official site
LifeMD attaches a $149/month program fee to medication pricing; its compounded tirzepatide all-in figure ($597) is the highest in our index, though its insurance-navigation pathway for brand products is a genuine strength.
It does not publicly name its compounding pharmacy; the record shows Partner pharmacies, so who actually makes the medication cannot be independently verified; commitment terms are Month-to-month; cancellation is Cancel anytime; availability is stated as 50 states.
Evidence: provider-stated — taken from the provider's own published pages; checkout capture pending, captured . Source — lifemd.com pricing capture 2026-08-05
Watch: Highest all-in compounded tirzepatide in the index; the value case rests on clinical service and insurance help, not price.
What neither record tells you
Yucca Health does not publish
- no published twelve-month tirzepatide rate
- no published twelve-month semaglutide rate
- no named compounding pharmacy
- no state-by-state availability list — it says Most US states
LifeMD does not publish
- no published twelve-month tirzepatide rate
- no published twelve-month semaglutide rate
- no named compounding pharmacy
Ask Yucca Health and LifeMD for each of those in writing before enrolling. A gap is not evidence of a problem; it does mean nothing can be checked against it.
What would change this answer
Neither program publishes a promotional rate with an end date, a prepaid term, or a price we have flagged for re-verification, so the comparison above is as stable as this dataset gets.
Which one suits which reader
On the lowest standing monthly rate for tirzepatide, Yucca Health Official site wins this matchup. If you want to be able to pause without still paying, yucca health carries no membership.
Both figures should be checked at the provider's own checkout before you pay. Yucca Health's tirzepatide price is provider-stated as of 2026-08-05; LifeMD's is provider-stated as of 2026-08-05.
Questions
Is Yucca Health or LifeMD cheaper for tirzepatide?
Yucca Health is cheaper on all-in monthly cost at 10 mg/week: $258 against $746, a difference of $488 a month. All-in means the medication plus every mandatory recurring fee.
What is the twelve-month cost of Yucca Health versus LifeMD?
Yucca Health works out to $3,096 across twelve months and LifeMD to $8,952, on the plan terms each publishes.
Does Yucca Health or LifeMD raise the price as the dose goes up?
Yucca Health: no, it charges one flat rate at every dose. LifeMD: no, it charges one flat rate at every dose. Where one program is flat and the other is tiered, the cheaper of the two can change as you titrate upward.
How many ways do Yucca Health and LifeMD differ?
4 of the eight dimensions this site records: all-in monthly, twelve-month cost, dose policy, membership, shipping, commitment, cancellation terms and evidence status.
Which of Yucca Health and LifeMD names its pharmacy?
Neither. Yucca Health records Partner 503A pharmacies and LifeMD records Partner pharmacies. Without a named pharmacy, neither program's licensing or inspection history can be checked before you order.
How well evidenced are the Yucca Health and LifeMD prices?
Yucca Health's tirzepatide figure is provider-stated — taken from the provider's own published pages; checkout capture pending — captured 2026-08-05. LifeMD's is provider-stated, captured 2026-08-05. Evidence status is worth fifteen points in the Value Score, so it is priced in rather than mentioned as an aside.
Which is cheaper for semaglutide?
Yucca Health, at $146 a month all-in against $497 at 2.4 mg/week. The two programs do not necessarily lead on both medications.
Official sources: Yucca Health official site · LifeMD official site. Compounded tirzepatide and semaglutide are not FDA-approved products.